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J Clin Gastroenterol. 2019 Jan;53(1):79   Artigo on-line
Remission of Marginal Zone Lymphoma After HCV Eradication With New Direct Antiviral Agents
Andrade P, Príncipe F, Macedo G
Clin Gastroenterol Hepatol. 2019 Jan;17(1):54-64.e1 Ver Resumo  |   Artigo on-line
Range of Normal Liver Stiffness and Factors Associated With Increased Stiffness Measurements in Apparently Healthy Individuals
Bazerbachi F, Haffar S, Wang Z, Cabezas J, Arias-Loste MT, Crespo J, Darwish-Murad S, Ikram MA, Olynyk JK, Gan E, Petta S, Berzuini A, Prati D, de Lédinghen V, Wong VW, Del Poggio P, Chávez-Tapia NC, Chen YP, Cheng PN, Yuen MF, Das K, Chowdhury A, Caballeria L, Fabrellas N, Ginès P, Kumar M, Sarin SK, Conti F, Andreone P, Sirli R, Cortez-Pinto H, Carvalhana S, Sugihara T, Kim SU, Parikh P, Chayama K, Corpechot C, Kim KM, Papatheodoridis G, Alsebaey A, Kamath PS, Murad MH, Watt KD
Helicobacter. 2018 Aug;23(4):e12493. Ver Resumo  |   Artigo on-line
Helicobacter pylori antibiotic resistance in Portugal: Systematic review and meta-analysis.
Lopo I, Libânio D, Pita I, Dinis-Ribeiro M, Pimentel-Nunes P

BACKGROUND: Portugal presents both a high prevalence of Helicobacter pylori (Hp) infection and a high prevalence of antibiotic resistance. However, conclusive data on its magnitude are lacking. We aimed at summarizing the existing data. MATERIALS AND METHODS: A systematic review was conducted after searching in two databases (PubMed and SciELO). Meta-analysis was performed, and comparison of resistance rates between children and adults and by type of resistance (primary and secondary) was made. RESULTS: Eight cross-sectional studies assessing Hp resistance to antibiotics were included. Overall resistance rates were as follows: clarithromycin (CLA) 42% (95% CI: 30-54), metronidazole (MTZ) 25% (95% CI: 15-38), ciprofloxacin (CIP) 9% (95% CI: 3-18), levofloxacin (LVX) 18% (95% CI: 2-42), tetracycline (TTC) 0.2% (95% CI: 0-1), and amoxicillin (AMX) 0.1% (95% CI: 0-0.2). Multidrug resistance was also an important problem, with the following global resistance rates: CLA plus MTZ of 10% (adults 20% (95% CI: 15-26) vs children 6% (95% CI: 4-9)) and CLA plus CIP of 2% (primary resistance in children's group). High secondary resistance rates were found for all antibiotics. Resistance was higher among adults for all antibiotics, except CLA that had high resistance levels both among adults and children (42% 95% CI: 14-71 and 40% 95% CI: 33-47). CONCLUSIONS: Hp resistance to the most widely used antibiotics is high in Portugal. Accordingly, our results suggest that the best therapeutic strategy for Hp in Portugal may be quadruple therapy with bismuth for adults and triple therapy including AMX plus MTZ or bismuth-based therapy for children.
Rev Esp Enferm Dig. 2018 Feb;110(2):109-114 Ver Resumo  |   Artigo on-line
Anal cytology, histopathology and anoscopy in an anal dysplasia screening program: is anal cytology enough?
Silva M, Peixoto A, Sarmento JA, Coelho R, Macedo G
Rev Esp Enferm Dig. 2018 Feb;110(2):123 Ver Resumo  |   Artigo on-line
Spontaneous intramural intestinal hemorrhage due to anticoagulation therapy
Ribeiro H, Azevedo R, Pereira E, Banhudo A
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